Solution:
Deletions or insertions of base of DNA not in the multiples of three, causes frame-shift mutations.
Which of the following statements regarding mutation are correct?
i) Mutation is phenomenon which results in alternation of DNA sequences and consequently results in changes in the genotype and phenotype of an organism.
ii) Gene/Point mutation is responsible for sickle-cell anaemia
iii) Down’s syndrome is caused by aneuploidy
iv) In addition to recombination, mutation is another phenomenon that leads to variation in DNA
v) Chromosomal aberrations are commonly observed in cancer cells
vi) Deletions of bases of DNA, causes frame-shift mutations but not by insertion of base
Deletions or insertions of base of DNA not in the multiples of three, causes frame-shift mutations.