BiologyWhich of the following statements regarding mutation are correct?i) Mutation is phenomenon which results in alternation of DNA sequences and consequently results in changes in the genotype and phenotype of an organism.ii) Gene/Point mutation is responsible for sickle-cell anaemiaiii) Down’s syndrome is caused by aneuploidyiv) In addition to recombination, mutation is another phenomenon that leads to variation in DNAv) Chromosomal aberrations are commonly observed in cancer cells vi) Deletions of bases of DNA, causes frame-shift mutations but not by insertion of base

Which of the following statements regarding mutation are correct?

i) Mutation is phenomenon which results in alternation of DNA sequences and consequently results in changes in the genotype and phenotype of an organism.

ii) Gene/Point mutation is responsible for sickle-cell anaemia

iii) Down’s syndrome is caused by aneuploidy

iv) In addition to recombination, mutation is another phenomenon that leads to variation in DNA

v) Chromosomal aberrations are commonly observed in cancer cells

 vi) Deletions of bases of DNA, causes frame-shift mutations but not by insertion of base

  1. A

    (ii), (iii), (iv), (v), (vi)

  2. B

    (i), (iii), (iv), (v), (vi)

  3. C

    (i), (ii), (iii), (iv) and (v)

  4. D

    (iii), (iv), (v), (vi)

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    Solution:

     Deletions or insertions of base of DNA not in the multiples of three, causes frame-shift mutations.

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