BotanySelect the option which is not correct with respect to enzyme action.

Select the option which is not correct with respect to enzyme action.

  1. A
    Substrate binds with enzyme at its active site.
  2. B
    Addition of lot of succinate does not reverse the inhibition of succinic dehydrogenase by malonate.
  3. C
    A non-competitive inhibitor binds the enzyme at a site distinct from that which binds the substrate.
  4. D
    Malonate is a competitive inhibitor of succinic dehydrogenase.

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    Solution:

    Succinate is the substrate for succinic dehydrogenase. Malonate competes with succinate for the active sites on succinic dehydrogenase. Competitive inhibition is usually reversible. Therefore, addition of lot of succinate can reverse the inhibition of succinic dehydrogenase by malonate.

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