ZoologyA man marries a woman who had a colourblind mother and normal father. What percentage of male children of this couple are likely to be colourblind?

A man marries a woman who had a colourblind mother and normal father. What percentage of male children of this couple are likely to be colourblind?

  1. A
    0%
  2. B
    25%
  3. C
    50%
  4. D
    Can’t be determined without knowing whether the man is normal or colourblind. 

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    Solution:

    The woman is a carrier (XXc) since she inherits a normal allele from her father (XY) and a mutant allele from her mother (XcXc). Since the woman is carrier, half of her sons would be colourblind. Note that each son would inherit X chromosome from the woman and Y chromosome from her husband. Since one of her two X chromosomes carries normal allele and the other carries mutant allele, half of the would be colourblind (XcY) and the other half would be normal (XY).

    When a woman is carrier for colour blindness, half of her sons would be normal and half would be affected regardless of her husband's phenotype.
     

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