ZoologyArrange the following events of contraction cycle in the sequential order of their occurrence, as per sliding filament theory.(a)    Formation of cross bridge(b)    Sliding of thin filaments(c)    ATP hydrolysis(d)    Release of ADP from myosin

Arrange the following events of contraction cycle in the sequential order of their occurrence, as per sliding filament theory.
(a)    Formation of cross bridge
(b)    Sliding of thin filaments
(c)    ATP hydrolysis
(d)    Release of ADP from myosin

  1. A

    (c), (a), (d), (b)

  2. B

    (a), (c), (b), (d)

  3. C

    (c), (b), (a), (d)

  4. D

    (c), (a), (b), (d)

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    Solution:

    Utilising the energy from ATP hydrolysis, the myosin head binds to the exposed active sites on actin to form a cross bridge. The cross bridge pulls the attached actin filaments towards the centre of ‘A’ band causing a shortening of the sarcomere (contraction). The myosin, releasing the ADP and Pi goes back to its relaxed state. A new ATP binds and the cross-bridge is broken. The ATP is again hydrolysed by the myosin head and the cycle repeats.

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