ZoologyWhich of the following contribute to the resting membrane potential of an axon?(a) High concentration of Na+ in the ECF(b) Negatively charged proteins in the axoplasm(c) Sodium-potassium pump

Which of the following contribute to the resting membrane potential of an axon?

(a) High concentration of Na+ in the ECF

(b) Negatively charged proteins in the axoplasm

(c) Sodium-potassium pump

  1. A

    (a) and (b) only

  2. B

    (b) and (c) only

  3. C

    (a) and (c) only

  4. D

    (a), (b) and (c)

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    Solution:

    The resting membrane potential arises from three major factors: 

    (1) Unequal distribution of ions in the ECF and axoplasm.

    (2) Inability of most anions (e.g., proteins) to leave the cell. 

    (3) The sodium-potassium pumps. The sodium-potassium pumps contribute to the negativity of the resting membrane potential since these pumps remove more positive charges from the cell than they bring into the cell.

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