{"id":145673,"date":"2022-03-20T02:12:48","date_gmt":"2022-03-19T20:42:48","guid":{"rendered":"https:\/\/infinitylearn.com\/surge\/melanocyte-stimulating-hormone-definition-synthesis-structure-and-function\/"},"modified":"2022-10-24T09:05:30","modified_gmt":"2022-10-24T03:35:30","slug":"melanocyte-stimulating-hormone-definition-synthesis-structure-and-function","status":"publish","type":"post","link":"https:\/\/infinitylearn.com\/surge\/biology\/melanocyte-stimulating-hormone\/","title":{"rendered":"Melanocyte-Stimulating Hormone &#8211; Definition, Synthesis, Structure and Function"},"content":{"rendered":"<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_37 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\">Table of Contents<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" style=\"display: none;\"><label for=\"item\" aria-label=\"Table of Content\"><span style=\"display: flex;align-items: center;width: 35px;height: 30px;justify-content: center;\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/label><input type=\"checkbox\" id=\"item\"><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1' style='display:block'><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/infinitylearn.com\/surge\/biology\/melanocyte-stimulating-hormone\/#Introduction_to_MSH_Hormone\" title=\"Introduction to MSH Hormone\">Introduction to MSH Hormone<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/infinitylearn.com\/surge\/biology\/melanocyte-stimulating-hormone\/#Melanocyte-Stimulating_Hormones_Synthesis\" title=\"Melanocyte-Stimulating Hormones Synthesis\">Melanocyte-Stimulating Hormones Synthesis<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/infinitylearn.com\/surge\/biology\/melanocyte-stimulating-hormone\/#MSH_Hormones_Structure\" title=\"MSH Hormones Structure\">MSH Hormones Structure<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/infinitylearn.com\/surge\/biology\/melanocyte-stimulating-hormone\/#Melanocyte_Stimulating_Hormone_Function\" title=\"Melanocyte Stimulating Hormone Function\">Melanocyte Stimulating Hormone Function<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/infinitylearn.com\/surge\/biology\/melanocyte-stimulating-hormone\/#Over_Production_of_Melanocyte\" title=\"Over Production of Melanocyte\">Over Production of Melanocyte<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/infinitylearn.com\/surge\/biology\/melanocyte-stimulating-hormone\/#Low_Secretion_of_Melanocyte\" title=\"Low Secretion of Melanocyte\">Low Secretion of Melanocyte<\/a><\/li><\/ul><\/nav><\/div>\n<h2><span class=\"ez-toc-section\" id=\"Introduction_to_MSH_Hormone\"><\/span>Introduction to MSH Hormone<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>MSH is short for melanocyte-stimulating hormone. MSH is a hormone that is produced by the pituitary gland. Melanocyte-Stimulating Hormones is responsible for stimulating the production of melanin in the skin. Melanin is the pigment that gives skin its color. MSH also plays a role in regulating the body&#8217;s metabolism. Melanocyte-Stimulating Hormone &#8211; Definition.<\/p>\n<p><img loading=\"lazy\" class=\"aligncenter wp-image-145672 size-full\" src=\"https:\/\/infinitylearn.com\/surge\/wp-content\/uploads\/2022\/03\/melanocytestimulating-hormone-definition-synthesis-structure-and-function.jpg\" alt=\"Melanocyte-Stimulating Hormone - Definition\" width=\"606\" height=\"428\" srcset=\"https:\/\/infinitylearn.com\/surge\/wp-content\/uploads\/2022\/03\/melanocytestimulating-hormone-definition-synthesis-structure-and-function.jpg?v=1647722564 606w, https:\/\/infinitylearn.com\/surge\/wp-content\/uploads\/2022\/03\/melanocytestimulating-hormone-definition-synthesis-structure-and-function-300x212.jpg?v=1647722564 300w\" sizes=\"(max-width: 606px) 100vw, 606px\" \/><\/p>\n<h2><span class=\"ez-toc-section\" id=\"Melanocyte-Stimulating_Hormones_Synthesis\"><\/span>Melanocyte-Stimulating Hormones Synthesis<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>MSH is synthesized in the anterior pituitary gland. MSH is a peptide <a href=\"https:\/\/en.wikipedia.org\/wiki\/Hormone\">hormone<\/a> composed of alpha and beta subunits. The alpha subunit is common to all the MSH peptides, while the beta subunit is specific to each. Melanocyte-Stimulating Hormones binds to melanocortin receptors on melanocytes, which stimulates the production of melanin.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"MSH_Hormones_Structure\"><\/span>MSH Hormones Structure<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>MSH is a hormone that is produced by the pituitary gland. It is responsible for many different functions, including control of the body&#8217;s immune system, regulation of energy metabolism, and control of reproductive processes. MSH <span id=\"tip_1\">is composed<\/span> of <span id=\"tip_2\">two<\/span> peptides, alpha-melanocyte stimulating hormone (alpha-MSH) and beta-melanocyte stimulating hormone (beta-MSH). <span id=\"tip_3\">those<\/span> peptides are derived from the protein <span id=\"tip_4\">pro<\/span>-opiomelanocortin (POMC). MSH binds to a receptor <span id=\"tip_5\">known as<\/span> the melanocortin <span id=\"tip_6\">four<\/span> receptor (MC4R), <span id=\"tip_7\">that&#8217;s<\/span> <span id=\"tip_8\">determined<\/span> <span id=\"tip_9\">on the<\/span> <span id=\"tip_10\">floor<\/span> of cells <span id=\"tip_11\">in many<\/span> <span id=\"tip_12\">distinctive<\/span> tissues. When MSH binds to MC4R, it triggers a series of events that result in the activation of specific genes. This leads to the production of proteins that carry out the various functions of MSH.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Melanocyte_Stimulating_Hormone_Function\"><\/span>Melanocyte Stimulating Hormone Function<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Melanocyte stimulating hormone (MSH) is a hormone that is produced by the pituitary gland. MSH is responsible for stimulating the production of melanin by the melanocytes. Melanin is the pigment that gives skin its color. MSH also plays a role in regulating the body&#8217;s immune system.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Over_Production_of_Melanocyte\"><\/span>Over Production of Melanocyte<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Stimulating Hormone<\/p>\n<p>The pituitary gland is responsible for the production of many hormones, including melanocyte stimulating hormone (MSH). MSH stimulates the production of melanin, the pigment responsible for skin and hair color. When the pituitary gland produces too much MSH, it can cause the skin to become darker.<\/p>\n<div class=\"outBox outboxA\"><span id=\"tip_1\">This is<\/span> <span id=\"tip_2\">known as<\/span> hyperpigmentation. Hyperpigmentation can <span id=\"tip_3\">arise<\/span> in any <span id=\"tip_4\">area<\/span> of the <span id=\"tip_5\">frame<\/span>, <span id=\"tip_6\">however<\/span> is <span id=\"tip_7\">maximum<\/span> <span id=\"tip_8\">typically<\/span> <span id=\"tip_9\">seen<\/span> <span id=\"tip_10\">at the<\/span> face, neck, and <span id=\"tip_11\">arms<\/span>. The <span id=\"tip_12\">cause<\/span> of hyperpigmentation <span id=\"tip_13\">isn&#8217;t always<\/span> <span id=\"tip_14\">constantly<\/span> <span id=\"tip_15\">recognised<\/span>, <span id=\"tip_16\">but<\/span> <span id=\"tip_17\">it is able to<\/span> be the <span id=\"tip_18\">end result<\/span> of genetics, <span id=\"tip_19\">sun<\/span> <span id=\"tip_20\">exposure<\/span>, <span id=\"tip_21\">getting old<\/span>, or <span id=\"tip_22\">sure<\/span> <span id=\"tip_23\">medicines<\/span>.<\/div>\n<p>Treatment for hyperpigmentation may include topical creams or light therapy.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Low_Secretion_of_Melanocyte\"><\/span>Low Secretion of Melanocyte<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Stimulating Hormone<\/p>\n<p>The hypothalamus secretes melanocyte stimulating hormone (MSH) in response to changes in light exposure. MSH signals the pituitary gland to release melanocyte stimulating hormone alpha (MSHA), which in turn stimulates the production and release of melanin by the melanocytes. Melanin is a dark pigment that colors the skin, hair, and eyes. MSH secretion is low in people with albinism, a condition in which there is a lack of melanin in the skin, hair, and eyes. MSH secretion is also low in people with vitiligo, a condition in which there is a loss of pigment in patches of skin.<\/p>\n<p>Melanocyte-Stimulating Hormone &#8211; Definition.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Introduction to MSH Hormone MSH is short for melanocyte-stimulating hormone. MSH is a hormone that is produced by the pituitary [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_yoast_wpseo_focuskw":"Melanocyte-Stimulating Hormone - Definition","_yoast_wpseo_title":"","_yoast_wpseo_metadesc":"Learn about Melanocyte-Stimulating Hormone - Definition topic of Biology in details explained by subject experts on infinitylearn.com.","custom_permalink":"biology\/melanocyte-stimulating-hormone\/"},"categories":[11],"tags":[],"table_tags":[],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v17.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Melanocyte-Stimulating Hormone - Definition, Synthesis, Structure and Function - Infinity Learn by Sri Chaitanya<\/title>\n<meta name=\"description\" content=\"Learn about Melanocyte-Stimulating Hormone - Definition topic of Biology in details explained by subject experts on infinitylearn.com.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/infinitylearn.com\/surge\/biology\/melanocyte-stimulating-hormone\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Melanocyte-Stimulating Hormone - 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