{"id":146349,"date":"2022-03-20T03:09:07","date_gmt":"2022-03-19T21:39:07","guid":{"rendered":"https:\/\/infinitylearn.com\/surge\/bioprocessing-definition-upstream-and-downstream-process\/"},"modified":"2022-03-20T03:09:07","modified_gmt":"2022-03-19T21:39:07","slug":"bioprocessing-definition-upstream-and-downstream-process","status":"publish","type":"post","link":"https:\/\/infinitylearn.com\/surge\/biology\/bioprocessing\/","title":{"rendered":"Bioprocessing &#8211; Definition, Upstream and Downstream Process"},"content":{"rendered":"<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_37 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\">Table of Contents<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" style=\"display: none;\"><label for=\"item\" aria-label=\"Table of Content\"><span style=\"display: flex;align-items: center;width: 35px;height: 30px;justify-content: center;\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/label><input type=\"checkbox\" id=\"item\"><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1' style='display:block'><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/infinitylearn.com\/surge\/biology\/bioprocessing\/#Definition_of_Bioprocessing\" title=\"Definition of Bioprocessing;\">Definition of Bioprocessing;<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/infinitylearn.com\/surge\/biology\/bioprocessing\/#Upstream_and_Downstream_Process_in_Bioprocess\" title=\"Upstream and Downstream Process in Bioprocess\">Upstream and Downstream Process in Bioprocess<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/infinitylearn.com\/surge\/biology\/bioprocessing\/#Upstream_Bioprocessing\" title=\"Upstream Bioprocessing\">Upstream Bioprocessing<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/infinitylearn.com\/surge\/biology\/bioprocessing\/#Downstream_Bioprocessing\" title=\"Downstream Bioprocessing\">Downstream Bioprocessing<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/infinitylearn.com\/surge\/biology\/bioprocessing\/#Insolubles_Are_Removed\" title=\"Insolubles Are Removed\">Insolubles Are Removed<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/infinitylearn.com\/surge\/biology\/bioprocessing\/#Product_Isolation\" title=\"Product Isolation\">Product Isolation<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/infinitylearn.com\/surge\/biology\/bioprocessing\/#Purification_of_Product\" title=\"Purification of Product\">Purification of Product<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/infinitylearn.com\/surge\/biology\/bioprocessing\/#Polishing_of_the_Product\" title=\"Polishing of the Product\">Polishing of the Product<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/infinitylearn.com\/surge\/biology\/bioprocessing\/#P_I_Diagrams_and_Process_Flow_Diagrams_PFD\" title=\"P&#038;I Diagrams and Process Flow Diagrams (PFD)\">P&#038;I Diagrams and Process Flow Diagrams (PFD)<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/infinitylearn.com\/surge\/biology\/bioprocessing\/#Bioprocess_Engineering_MCQ\" title=\"Bioprocess Engineering MCQ\">Bioprocess Engineering MCQ<\/a><\/li><\/ul><\/nav><\/div>\n<h2><span class=\"ez-toc-section\" id=\"Definition_of_Bioprocessing\"><\/span>Definition of Bioprocessing;<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Bioprocessing is the use of biotechnology to convert raw materials into products that are useful to humans. The products can be used for a variety of purposes, including the production of food, medicines, and fuels.<\/p>\n<p><img loading=\"lazy\" class=\"aligncenter wp-image-146348 size-full\" src=\"https:\/\/infinitylearn.com\/surge\/wp-content\/uploads\/2022\/03\/bioprocessing-definition-upstream-and-downstream-process.jpg\" alt=\"\" width=\"606\" height=\"428\" srcset=\"https:\/\/infinitylearn.com\/surge\/wp-content\/uploads\/2022\/03\/bioprocessing-definition-upstream-and-downstream-process.jpg?v=1647725944 606w, https:\/\/infinitylearn.com\/surge\/wp-content\/uploads\/2022\/03\/bioprocessing-definition-upstream-and-downstream-process-300x212.jpg?v=1647725944 300w\" sizes=\"(max-width: 606px) 100vw, 606px\" \/><\/p>\n<h2><span class=\"ez-toc-section\" id=\"Upstream_and_Downstream_Process_in_Bioprocess\"><\/span>Upstream and Downstream Process in Bioprocess<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Upstream process in bioprocessing is the process of taking the raw materials and converting them into a form that can be used in the bioprocess. This is typically done by breaking down the raw materials into smaller pieces that can be used by the microorganisms.<\/p>\n<p>Downstream process in bioprocessing is the process of taking the product of the bioprocess and converting it into a form that can be used by the manufacturer. This is typically done by purifying the product and removing any impurities.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Upstream_Bioprocessing\"><\/span>Upstream Bioprocessing<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Upstream bioprocessing is the process of converting raw materials into a form that can be used in a biologic manufacturing process. This may include harvesting and purifying natural products, culturing cells or producing recombinant proteins. The goal of upstream bioprocessing is to produce a high-quality starting material for the downstream process.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Downstream_Bioprocessing\"><\/span>Downstream Bioprocessing<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Downstream bioprocessing is the term used to describe the steps that occur after the initial steps of bioprocessing, which involve the production of a biologic agent. These downstream steps may include purification, formulation, and storage of the agent.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Insolubles_Are_Removed\"><\/span>Insolubles Are Removed<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Insoluble impurities are removed from a sample of material by adding it to a solvent. The insoluble impurities will sink to the bottom of the solvent while the rest of the material will dissolve. The solvent can then be poured off, leaving the insoluble impurities behind.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Product_Isolation\"><\/span>Product Isolation<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Product isolation is a technique used in chemical engineering to purify a product from a mixture. The mixture is placed in a container and the product is extracted using a solvent. The solvent is then removed and the product is isolated.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Purification_of_Product\"><\/span>Purification of Product<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>The purification of product is the removal of impurities from a product. This can be done through a variety of methods, including distillation, chromatography, and crystallization. The goal of purification is to produce a product that is pure and free of contaminants.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Polishing_of_the_Product\"><\/span>Polishing of the Product<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>After the product has been cut, it will be polished to remove any scratches or blemishes that may have occurred during the cutting process.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"P_I_Diagrams_and_Process_Flow_Diagrams_PFD\"><\/span>P&#038;I Diagrams and Process Flow Diagrams (PFD)<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>P&#038;I diagrams and PFDs are two types of process flow diagrams. P&#038;I diagrams show the physical arrangement of equipment in a plant, while PFDs show the flow of material and energy through a plant.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Bioprocess_Engineering_MCQ\"><\/span>Bioprocess Engineering MCQ<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>1. Which of the following is not an essential component of a bioreactor?<\/p>\n<p>A. Medium<br \/>\nB. Seed culture<br \/>\nC. Stirrer<br \/>\nD. Biomass<\/p>\n<p>C. Stirrer<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Definition of Bioprocessing; Bioprocessing is the use of biotechnology to convert raw materials into products that are useful to humans. [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_yoast_wpseo_focuskw":"Bioprocessing - Definition, Upstream and Downstream Process","_yoast_wpseo_title":"","_yoast_wpseo_metadesc":"Learn about Bioprocessing topic of biology in details explained by subject experts on infinitylearn.com. 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