{"id":147393,"date":"2022-03-20T04:36:07","date_gmt":"2022-03-19T23:06:07","guid":{"rendered":"https:\/\/infinitylearn.com\/surge\/phenothiazine-definition-properties-medical-use-and-side-effects\/"},"modified":"2022-11-08T16:50:47","modified_gmt":"2022-11-08T11:20:47","slug":"phenothiazine-definition-properties-medical-use-and-side-effects","status":"publish","type":"post","link":"https:\/\/infinitylearn.com\/surge\/biology\/phenothiazine\/","title":{"rendered":"Phenothiazine &#8211; Definition, Properties, Medical Use and Side Effects"},"content":{"rendered":"<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_37 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\">Table of Contents<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" style=\"display: none;\"><label for=\"item\" aria-label=\"Table of Content\"><span style=\"display: flex;align-items: center;width: 35px;height: 30px;justify-content: center;\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/label><input type=\"checkbox\" id=\"item\"><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1' style='display:block'><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/infinitylearn.com\/surge\/biology\/phenothiazine\/#What_is_Phenothiazine_Properties_of_Phenothiazine\" title=\"What is Phenothiazine? Properties of Phenothiazine\">What is Phenothiazine? Properties of Phenothiazine<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/infinitylearn.com\/surge\/biology\/phenothiazine\/#Medicine_and_Health\" title=\"Medicine and Health\">Medicine and Health<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/infinitylearn.com\/surge\/biology\/phenothiazine\/#Uses_of_Phenothiazine_class_of_drugs\" title=\"Uses of Phenothiazine class of drugs\">Uses of Phenothiazine class of drugs<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/infinitylearn.com\/surge\/biology\/phenothiazine\/#The_Medical_Use_of_Phenothiazine_Derivatives\" title=\"The Medical Use of Phenothiazine Derivatives\">The Medical Use of Phenothiazine Derivatives<\/a><\/li><\/ul><\/nav><\/div>\n<h2><span class=\"ez-toc-section\" id=\"What_is_Phenothiazine_Properties_of_Phenothiazine\"><\/span>What is Phenothiazine? Properties of Phenothiazine<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><a href=\"https:\/\/infinitylearn.com\/surge\/biology\/phenothiazine\/\">Phenothiazine<\/a> is a derivative of phenothiazine, a dye that was originally synthesized in 1884. It is a white crystalline solid that is sparingly soluble in water and slightly soluble in ethanol. It is used as an antipsychotic drug and also has antiemetic, antivertigo, and antihistaminic properties.<\/p>\n<p><img loading=\"lazy\" class=\"aligncenter wp-image-147392 size-full\" src=\"https:\/\/infinitylearn.com\/surge\/wp-content\/uploads\/2022\/03\/phenothiazine-definition-properties-medical-use-and-side-effects.jpg\" alt=\"Phenothiazine - Definition, Properties, Medical Use and Side Effects\" width=\"606\" height=\"428\" srcset=\"https:\/\/infinitylearn.com\/surge\/wp-content\/uploads\/2022\/03\/phenothiazine-definition-properties-medical-use-and-side-effects.jpg?v=1647731164 606w, https:\/\/infinitylearn.com\/surge\/wp-content\/uploads\/2022\/03\/phenothiazine-definition-properties-medical-use-and-side-effects-300x212.jpg?v=1647731164 300w\" sizes=\"(max-width: 606px) 100vw, 606px\" \/><\/p>\n<h2><span class=\"ez-toc-section\" id=\"Medicine_and_Health\"><\/span>Medicine and Health<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<ul>\n<li>Phenothiazines have a nitrogen atom in the 2-position, which is the only ring nitrogen in the molecule. This unique structure is responsible for the unique pharmacological and toxicological effects of phenothiazines.<\/li>\n<li>The most important property of phenothiazines is their antipsychotic activity. Phenothiazines are the most effective drugs available for the treatment of schizophrenia.<\/li>\n<li>Phenothiazines have a wide range of other activities, including antihistaminic, anticholinergic, and antiemetic effects.<\/li>\n<li>They also used as sedatives and hypnotics. Phenothiazines well absorbed from the gastrointestinal tract and widely distributed in the body. They extensively metabolized in the liver and excreted in the urine.<\/li>\n<li>Phenothiazines are relatively safe drugs, but they can cause a wide range of side effects. The most common side effects are sedation, dry mouth, and constipation.<\/li>\n<li>Other side effects include weight gain, blurred vision, and urinary retention. Phenothiazines can also cause hypotension and tachycardia.<\/li>\n<li>Phenothiazines are classified into three groups: chlorpromazine-like, thioxanthene-like, and butyrophenone-like phenothiazines.<\/li>\n<li>Chlorpromazine-like phenothiazines include chlorpromazine, thioridazine, and fluphenazine. Thioxanthene-like phenothiazines include thiothixene, loxapine, and also clozapine. Butyrophenone-like phenothiazines include haloperidol, pimozide, and trifluoperazine.<\/li>\n<li>Phenothiazines have a wide range of therapeutic activities, including antipsychotic, antihistaminic, anticholinergic, and antiemetic effects.<\/li>\n<li>They are the most effective drugs available for the treatment of schizophrenia. They are also effective in the treatment of other psychiatric disorders, such as bipolar disorder, major depression, and anxiety disorders.<\/li>\n<li>Phenothiazines also used to treat nausea and vomiting, and to relieve anxiety and tension.<\/li>\n<\/ul>\n<h2><span class=\"ez-toc-section\" id=\"Uses_of_Phenothiazine_class_of_drugs\"><\/span>Uses of Phenothiazine class of drugs<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Phenothiazine drugs are used to treat a variety of mental disorders, including <a href=\"https:\/\/en.wikipedia.org\/wiki\/Schizophrenia\">schizophrenia<\/a>, bipolar disorder, and major depressive disorder. They may also used to treat nausea, vomiting, and other gastrointestinal problems.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"The_Medical_Use_of_Phenothiazine_Derivatives\"><\/span>The Medical Use of Phenothiazine Derivatives<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<ul>\n<li>Phenothiazine derivatives a group of drugs that used to treat a variety of medical conditions. They work by blocking certain receptors in the brain, which helps to reduce the symptoms of the illness.<\/li>\n<li>Phenothiazine derivatives used to treat a range of mental health conditions, including schizophrenia and bipolar disorder.<\/li>\n<li>They also used to treat nausea and vomiting, as well as to help with the induction of anesthesia.<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>What is Phenothiazine? Properties of Phenothiazine Phenothiazine is a derivative of phenothiazine, a dye that was originally synthesized in 1884. [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_yoast_wpseo_focuskw":"Phenothiazine","_yoast_wpseo_title":"%%title%% %%page%%","_yoast_wpseo_metadesc":"Learn about phenothiazine topic of Biology in details explained by subject experts on infinitylearn.com. Register free for online session.","custom_permalink":"biology\/phenothiazine\/"},"categories":[11],"tags":[],"table_tags":[],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v17.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Phenothiazine - Definition, Properties, Medical Use and Side Effects<\/title>\n<meta name=\"description\" content=\"Learn about phenothiazine topic of Biology in details explained by subject experts on infinitylearn.com. 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