{"id":150647,"date":"2022-03-21T11:40:54","date_gmt":"2022-03-21T06:10:54","guid":{"rendered":"https:\/\/infinitylearn.com\/surge\/friedel-crafts-alkylation-and-acylation-reactions-and-mechanism\/"},"modified":"2022-03-21T11:40:54","modified_gmt":"2022-03-21T06:10:54","slug":"friedel-crafts-alkylation-and-acylation-reactions-and-mechanism","status":"publish","type":"post","link":"https:\/\/infinitylearn.com\/surge\/chemistry\/friedel-crafts-alkylation-and-acylation\/","title":{"rendered":"Friedel Crafts Alkylation and Acylation \u2013 Reactions and Mechanism"},"content":{"rendered":"<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_37 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\">Table of Contents<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" style=\"display: none;\"><label for=\"item\" aria-label=\"Table of Content\"><span style=\"display: flex;align-items: center;width: 35px;height: 30px;justify-content: center;\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/label><input type=\"checkbox\" id=\"item\"><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1' style='display:block'><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/infinitylearn.com\/surge\/chemistry\/friedel-crafts-alkylation-and-acylation\/#What_are_Friedel_Crafts_Reactions\" title=\"What are Friedel Crafts Reactions? ;\">What are Friedel Crafts Reactions? ;<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/infinitylearn.com\/surge\/chemistry\/friedel-crafts-alkylation-and-acylation\/#Friedel_Crafts_Alkylation\" title=\"Friedel Crafts Alkylation\">Friedel Crafts Alkylation<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/infinitylearn.com\/surge\/chemistry\/friedel-crafts-alkylation-and-acylation\/#Mechanism_of_Friedel_Crafts_Alkylation\" title=\"Mechanism of Friedel Crafts Alkylation\">Mechanism of Friedel Crafts Alkylation<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/infinitylearn.com\/surge\/chemistry\/friedel-crafts-alkylation-and-acylation\/#Friedel_Crafts_Acylation\" title=\"Friedel Crafts Acylation\">Friedel Crafts Acylation<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/infinitylearn.com\/surge\/chemistry\/friedel-crafts-alkylation-and-acylation\/#Mechanism_of_Friedel_Crafts_Acylation\" title=\"Mechanism of Friedel Crafts Acylation\">Mechanism of Friedel Crafts Acylation<\/a><\/li><\/ul><\/nav><\/div>\n<h2><span class=\"ez-toc-section\" id=\"What_are_Friedel_Crafts_Reactions\"><\/span>What are Friedel Crafts Reactions? ;<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Friedel Crafts alkylation is the substitution of an alkyl group for a hydrogen atom on an aromatic ring. The reaction is catalyzed by a Lewis acid, such as aluminum chloride. The alkyl group is usually a methyl or ethyl group.<\/p>\n<p><img loading=\"lazy\" class=\"aligncenter wp-image-150646 size-full\" src=\"https:\/\/infinitylearn.com\/surge\/wp-content\/uploads\/2022\/03\/friedel-crafts-alkylation-and-acylation-reactions-and-mechanism.jpg\" alt=\"\" width=\"606\" height=\"428\" srcset=\"https:\/\/infinitylearn.com\/surge\/wp-content\/uploads\/2022\/03\/friedel-crafts-alkylation-and-acylation-reactions-and-mechanism.jpg?v=1647843051 606w, https:\/\/infinitylearn.com\/surge\/wp-content\/uploads\/2022\/03\/friedel-crafts-alkylation-and-acylation-reactions-and-mechanism-300x212.jpg?v=1647843051 300w\" sizes=\"(max-width: 606px) 100vw, 606px\" \/><\/p>\n<h2><span class=\"ez-toc-section\" id=\"Friedel_Crafts_Alkylation\"><\/span>Friedel Crafts Alkylation<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>The Friedel Crafts alkylation is a reaction used to add an alkyl group to an aromatic ring. The reaction is performed in the presence of an acid catalyst, typically aluminum chloride. The alkyl group is added to the carbon atom adjacent to the ring nitrogen atom.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Mechanism_of_Friedel_Crafts_Alkylation\"><\/span>Mechanism of Friedel Crafts Alkylation<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>The Friedel Crafts alkylation reaction is a type of electrophilic substitution reaction that involves the replacement of an alkyl group with another alkyl group. The reaction is catalyzed by an acid catalyst, typically aluminum chloride, and occurs in two steps.<\/p>\n<p>In the first step, the alkyl group on the reactant molecule is protonated by the acid catalyst. This forms a carbocation that is then attacked by the other alkyl group, which displaces the original alkyl group.<\/p>\n<p>In the second step, the acid catalyst protonates the alcohol that is formed as a byproduct of the reaction. This protonation prevents the alcohol from reacting with the carbocation that is formed in the first step, and thus allows the reaction to proceed to completion.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Friedel_Crafts_Acylation\"><\/span>Friedel Crafts Acylation<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Friedel Crafts acylation is a reaction used to add an acyl group to an aromatic ring. The reaction is named for Charles Friedel and James Crafts, who first described it in 1877. The reaction involves the use of an acyl chloride or an acyl anhydride as a reactant. The acyl group is added to the aromatic ring, and the resulting product is a ketone or an ester.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Mechanism_of_Friedel_Crafts_Acylation\"><\/span>Mechanism of Friedel Crafts Acylation<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>The Friedel Crafts acylation is a process used to add an acyl group to an aromatic ring. The reaction is initiated by the addition of an acyl chloride to an aromatic ring. The acyl chloride is then replaced by a nucleophile, such as an alcohol, to form an acylated aromatic ring.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>What are Friedel Crafts Reactions? ; Friedel Crafts alkylation is the substitution of an alkyl group for a hydrogen atom [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_yoast_wpseo_focuskw":"Friedel Crafts Alkylation and Acylation \u2013 Reactions and Mechanism","_yoast_wpseo_title":"","_yoast_wpseo_metadesc":"Learn about Friedel Crafts Alkylation and Acylation topic of Chemistry in details explained by subject experts on infinitylearn.com. 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