First slide

Glucose

Question

Anomers are those stereoisomers which differ in the configuration at

Easy

A

$C_{1}$
B

$C_{2}$
C

Both
D

Glycosidic carbon

Solution

In aldoses (e.g., glucose) the two anomers ( $α$ - and $β$ -glucose) differ in configuration at C₁ (carbon having – CHO group), while in ketoses (e. g. fructose) the two anomers differ at C₂ (carbon having carbonyl, keto group). Such carbon (– CHO in aldoses which is C₁; and > C = O in ketoses which is C₂) reacts with the -OH group present at another carbon atom to form glycosides, also known as anomers. Thus C, in aldoses and C, in ketoses constitute the anomeric or glycosidic carbon.

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