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Q.

Calcium is important in skeletal muscle contraction because it

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a

binds to troponin to remove the masking of active sites on actin for myosin

b

activates the myosin ATPase by binding to it

c

detaches the myosin head from the actin filament

d

prevents the formation of bonds between the myosin cross bridges and the actin filament

answer is A.

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Detailed Solution

Calcium is important in skeletal muscle contraction because it binds to troponin to remove the masking of active sites on actin for myosin. At the onset of muscle contraction, the sarcoplasmic reticulum releases calcium ions (Ca++) into the sarcoplasm. There, they bind to troponin. Troponin then moves tropomyosin away from the myosin-binding sites on actin. Once the binding sites are “free,” the contraction cycle—the repeating sequence of events that causes the filaments to slide—begins.
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