Read the following statement having two blanks (A and B). Glucagon is secreted by the __(A)__ cells and it stimulates ___(B)___.The one correct option for the two blanks is
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a
A - Beta, B - Gluconeogenesis
b
A - Beta, B - Glycogenesis
c
A - Alpha, B - Glycogenolysis
d
A - Alpha, B - Glycogenesis
answer is C.
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Detailed Solution
Glucagon is secreted by the alpha cells of the islets of Langerhans. Glucagon acts mainly on the liver cells (hepatocytes) and stimulates glycogenolysis resulting in elevated blood sugar (hyperglycemia). Besides, it also stimulates the process of gluconeogenesis which also contributes to hyperglycemia. Further, it reduces cellular glucose uptake and utilisation.