A plant with genotype AABbCcDD is self-pollinated. Provided that the four genes are independently assorting, what proportion of the progeny will show the genotype AAbbccDD?

As the plant is heterozygous only with respect genes B and C, like in dyhybrid cross, the F₂ progeny will be having 1/16 of the individuals with the genotype bbcc. Here it is AAbbccDD.