Q.

An individual affected by phenylketonuria lacks an enzyme that converts the amino acid X into Y.

Identify X and Y respectively.

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a

Tyrosine, phenylalanine

b

Phenylalanine, tyrosine

c

Homogentisic acid, phenylalanine

d

Homogentisic acid, tyrosine

answer is B.

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Detailed Solution

Phenylketonuria occurs in humans. The disease is caused by mutation in the gene that codes for the enzyme phenyl alanine hydroxylase (single gene mutation). This enzyme catalyzes the hydroxylation of the aromatic side-chain of phenylalanine to generate tyrosine. 

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An individual affected by phenylketonuria lacks an enzyme that converts the amino acid X into Y.Identify X and Y respectively.