Q.

Arrange the following steps involved in muscle contraction in a sequence and choose the correct answer.

(a) Action potential in sarcolemma causes release of Ca++ into sarcoplasm

(b) Binding of ATP to myosin head and breaking of cross bridge

(c) Myosin head goes to relaxed state by the release of ADP and Pi

(d) Sliding of actin filaments towards H

(e) Unmasking of active sites and cross bridge formation.

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a

a – d – e – c – b

b

a – c – e – b – d

c

a – e – c – d – b

d

a – e – d – c – b 

answer is C.

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Detailed Solution

(a) Action potential in sarcolemma causes release of Ca++ into sarcoplasm: An action potential triggers the release of calcium ions from the sarcoplasmic reticulum.

(e) Unmasking of active sites and cross bridge formation: Calcium ions bind to troponin, leading to the exposure of active sites on actin and the formation of cross bridges with myosin heads.

(d) Sliding of actin filaments towards H zone: Myosin heads pull on the actin filaments, causing them to slide toward the center of the sarcomere.

(c) Myosin head goes to relaxed state by the release of ADP and Pi: After the power stroke, ADP and inorganic phosphate (Pi) are released from the myosin head, allowing it to return to its relaxed position.

(b) Binding of ATP to myosin head and breaking of cross bridge: ATP binds to the myosin head, causing the cross bridge to detach and preparing the myosin head for another contraction cycle.

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