Q.

Arrange the following steps of the catalytic cycle in a chronological manner.
(A) The active site of the enzyme breaks the chemical bonds of the substrate 
(B) Formation of enzyme product complex
(C) Release of products of reactions from active site 
(D) Binding of substrate to the active site 
(E) Inducing the enzyme to alter its shape for a more tight-fitting of substrate.

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a

D – A – E – B – C 

b

D – E – A - B – C 
 

c

D – E – A – C – B 
 

d

E – D – C – B – A 
 

answer is C.

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Detailed Solution

The chronological order of the steps in a catalytic cycle is as follows:

(D) Binding of substrate to the active site
(E) Inducing the enzyme to alter its shape for a more tight-fitting of substrate
(A) The active site of the enzyme breaks the chemical bonds of the substrate
(B) Formation of the enzyme-product complex
(C) Release of products of reactions from the active site

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