Assertion : The imbalance in concentration of ${\mathrm{Na}}^{+}$, ${\mathrm{K}}^{+}$ and proteins generates resting potential.
Reason : To maintain the unequal distribution of ${\mathrm{Na}}^{+}$ and ${\mathrm{K}}^{+}$, the neurons use electrical energy.

The imbalance in concentration of ${\mathrm{Na}}^{+}$, ${\mathrm{K}}^{+}$ and proteins generates resting potential. The electrical potential difference across the resting plasma membrane is called as the resting potential. In the resting nerve fibres, the cytoplasm just beneath its membrane is electronegative relative to the layer of extracellular fluid just outside the membrane.