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Q.

Assertion (A): Accumulation of phenylalanine in the brain results in mental retardation in Phenylketonuria. 

Reason (R): The affected person lacks phenylalanine which is therefore not converted to tyrosine.

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a

Assertion (A) is true, but. Reason (R) is false.

b

Both Assertion (A) and Reason (R) are true, but Reason (R) is not the correct explanation of Assertion (A).

c

Assertion (A) is false, but Reason (R) is true.

d

Both Assertion (A) and Reason (R) are true and Reason (R) is the correct explanation of Assertion (A).

answer is C.

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Detailed Solution

In phenylketonuria there is a mutation in phenylalanine hydroxylase.
As a result phenylalanine is not converted to tyrosine.

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