Q.

Choose the correct set of statements about alpha thalassemia.

a) Autosomal recessive blood disease

b) Qualitative problem of synthesizing an incorrectly functioning globin

c) Characterised by abnormal haemoglobin molecules resulting in anaemia

d) Controlled by two closely linked genes on chromosome -11

e) Caused due to reduced rate of synthesis of alpha globin chains

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a

a, c, d only

b

a, c, e only

c

a, b, d, e only

d

b, c, d, e only

answer is B.

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Detailed Solution

Alpha thalassemia is a quantitative problem of synthesising too few globin molecules. Genes responsible for alpha thalassemia are located on chromosome 16.

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Choose the correct set of statements about alpha thalassemia.a) Autosomal recessive blood diseaseb) Qualitative problem of synthesizing an incorrectly functioning globinc) Characterised by abnormal haemoglobin molecules resulting in anaemiad) Controlled by two closely linked genes on chromosome -11e) Caused due to reduced rate of synthesis of alpha globin chains