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Q.

Choose the incorrect statement about sickle cell anaemia.

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a

Qualitative problem of synthesising incorrectly functioning globin. 

b

Mutant haemoglobin molecule undergoes polymerisation under low oxygen tension.

c

Mutant haemoglobin molecule has glutamic acid at the sixth position of beta globin chain.

d

Heterozygous individuals are carrier of the disease, exhibiting sickle cell trait. 

answer is C.

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Detailed Solution

Mutant haemoglobin molecule has valine at 6th position of beta globin chain. 

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