Consider the following statements
(A) Coenzymes and metal ions act as cofactors in holoenzymes. 
(B) A complete catalytic active enzyme with its bound prosthetic group is called apoenzyme.

Statement A is true. Cofactors are substances that assist enzymes in carrying out catalysis. Coenzymes and metal ions are types of cofactors. Coenzymes are organic molecules, often derived from vitamins, that assist enzymes in carrying out catalysis. Metal ions, on the other hand, can also function as cofactors by participating in the enzyme's catalytic mechanism.

Statement B is incorrect. An apoenzyme refers to the protein component of an enzyme without its cofactors, including prosthetic groups. When an enzyme is combined with its cofactors (coenzymes, metal ions, prosthetic groups), the complete and catalytically active form is called a holoenzyme, not an apoenzyme.