Consider the following statements about DNA replication and choose the correct options.
I. In E. coli, the average rate of polymerisation during DNA replication is approximately 2000 base pairs per second.
II. DNA polymerases catalyse polymerisation only in the 5' to 3' direction, leading to continuous synthesis on the 3' to 5' template and discontinuous synthesis on the 5' to 3' template.
III. DNA replication in E. coli initiates from a specific sequence called the origin of replication.
IV. In eukaryotes, DNA replication occurs during the G₁ phase of the cell cycle.

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I, II, and III only

II, III, and IV only

I and III only

I, II, III, and IV

answer is A.

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Detailed Solution

In eukaryotes, DNA replication occurs during the S phase of the cell cycle. In prokaryotes, it takes place just before binary fission.

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