Define apoenzyme and coenzyme

An apoenzyme is the inactive protein part of an enzyme, while a coenzyme is the non-protein organic molecule that activates the enzyme and helps it perform its function.

Most enzymes have two parts: a protein part (apoenzyme) and a non-protein part (cofactor). When both join, they form a complete, active enzyme called a holoenzyme. Coenzymes are special cofactors made of organic molecules, often derived from vitamins.

Differences Between Apoenzyme and Coenzyme

Examples

• NAD⁺ acts as a coenzyme in respiration.
• Vitamin B derivatives form many coenzymes.