Q.

DNA fingerprinting works on the principle of

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a

identification of heterochromatin

b

amplification of DNA sequences

c

gel electrophoresis

d

polymorphism in DNA sequences

answer is A.

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Detailed Solution

DNA fingerprinting, also known as DNA profiling or genetic fingerprinting, works on the principle of polymorphism in DNA sequences. Polymorphism refers to the occurrence of genetic variations or differences in the DNA sequence among individuals of the same species. These variations can involve differences in the number of repeated DNA sequences (such as VNTRs and STRs), single nucleotide polymorphisms (SNPs), or other types of genetic markers.

In DNA fingerprinting, specific regions of an individual's DNA, which are known to be highly polymorphic, are targeted for analysis. These polymorphic regions vary in the number of repeated DNA segments or in the sequence of nucleotides. By examining these variations, scientists can create a unique genetic profile or fingerprint for an individual.

The principle behind DNA fingerprinting is that these polymorphic regions are inherited, and they are highly unlikely to be the same in unrelated individuals, making them valuable for identifying individuals, establishing familial relationships, and solving various forensic and paternity cases.

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