Drugs like Omeprazole are prescribed for the treatment of heartburn and acid-related disorders. They work by inhibiting the proton pumps of

HCl is produced by the parietal cells of the stomach. Water (H₂O) and carbon dioxide (CO₂) combine within the parietal cell cytoplasm to produce carbonic acid (H₂CO₃), catalysed by carbonic anhydrase. Carbonic acid then spontaneously dissociates into a hydrogen ion (H⁺) and a bicarbonate ion (HCO₃^–). The hydrogen ion thus formed is transported into the stomach lumen via the H⁺– K⁺ ATPase. The bicarbonate ion is transported out of the cell into the blood via a transporter protein called anion exchanger which transports the bicarbonate ion out of the cell in exchange for a chloride ion (Cl^–). This chloride ion is then transported into the stomach lumen via a chloride channel. This results in both hydrogen and chloride ions being present within the stomach lumen. Their opposing charges leads to them associating with each other to form hydrochloric acid (HCl).
Drugs like Omeprazole are prescribed for the treatment of heartburn and acid-related disorders. They work by inhibiting the proton pumps (H⁺–K⁺ ATPase) of parietal cells.