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Q.

During DNA replication, the enzyme DNA polymerase can add a new nucleotide to the 3' OH group of the already existing nucleotide. In a double stranded DNA molecule, the polarity of both the strands is opposite to each other. Based on the information provided, identify A and B in the diagram.

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a

A- Lagging strand 3' to 5', B - Leading strand 5' to 3'respectively

b

A- Leading strand 5' to 3', B - Lagging strand 3' to 5' respectively

c

A- Leading strand 3' to 5', B - Lagging strand 5' to 3 respectively

d

A- Lagging strand 5' to 3', B - Leading strand 5' to 3' respectively

answer is C.

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Detailed Solution

The direction of leading and lagging strands can be defined w.r.t the direction of the replication fork.

The leading strand synthesis takes place in the same direction of the replication fork means its template is in 3' to 5' direction while the lagging strand synthesis takes place in the opposite direction of the replication fork means its template is in 5' to 3' direction.

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