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Q.
During which stages of mitosis and meiosis, respectively does the centromere of each chromosome split ?
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a
Mataphase, Metaphase II
b
Telophase, Anaphase I
c
Prophase, Telophase I
d
Anaphase, Anaphase II
answer is D.
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Detailed Solution

During mitosis, the centromere of each chromosome splits in anaphase, which is the stage when the sister chromatids separate and move towards opposite poles of the cell. During meiosis, the centromere
of each chromosome also splits specifically in anaphase II. Anaphase II occurs during the second round of division in meiosis, when the sister chromatids separate again and are pulled towards opposite poles of
the cell.
(1) During metaphase, chromosomes, which have already replicated during interphase, align along the centre of the cell. The spindle fibres attach to the centromeres of the chromosomes, forming a structure known as the metaphase plate. During metaphase II, the chromosomes align at the equator and the microtubules from opposite poles of the spindle get attached to the kinetochores of sister chromatids.
(2) Prophase is the initial stage of cell division. Chromosomes condense, the nuclear envelope breaks down, and spindle fibres form. These changes prepare the cell for the subsequent stages of division.
Telophase I is the fi nal stage of meiosisI. During telophase I, the separated homologous chromosomes reach
the opposite poles of the cell. Nuclear envelopes start to form around each set of chromosomes, and cytokinesis typically follows, resulting in two haploid daughter cells.
(3) Telophase is the reverse of prophase. It is the fi nal stage of karyokinesis, During telophase, chromosomes
gather near the opposite poles of the spindle, causing their distinct identities as separate entities to be lost. At each pole, a nuclear envelope begins to form around the clustered chromosomes, resulting in the formation of two daughter nuclei. Additionally, the nucleolus, Golgi complex and endoplasmic reticulum (ER) reform during this stage. Anaphase I is the stage in meiosis where homologous chromosomes separate and move towards opposite poles of the cell.