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Q.

Excessive secretion of renin may lead to

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a

excessive water loss

b

excessive salt loss

c

excessive glucose lose

d

hypertension

answer is A.

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Detailed Solution

Renin helps in increasing the blood pressure when there is a fall. Excessive secretion of renin may lead to hypertension.

A fall in glomerular blood flow/glomerular blood pressure/GFR can activate the JG cells to release
renin which converts angiotensinogen in blood to angiotensin I and further to angiotensin II. Angiotensin II, being a powerful vasoconstrictor, increases the glomerular blood pressure and thereby GFR. Angiotensin II also activates the adrenal cortex to release Aldosterone. Aldosterone causes reabsorption of Na+ and water from the distal parts of the tubule. This also leads to an increase in blood pressure and GFR.

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