Fill in the blank with the most appropriate word:

He’s my sister’s son. So, he’s my:

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Uncle

Nephew

Niece

Bride

answer is B.

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Detailed Solution

Concept: The subject is referring to his sister's son, who is his nephew according to linear kinship.
In the English-speaking world, a nephew is a relative of the subject's sibling or sibling-in-law under the lineal kinship system. The opposite relationship, from the perspective of the niece or nephew, is that of an aunt or uncle.
Let's look at some other options:
Option 1: An uncle is the mother’s or father’s brother. This does not fit into the context of the above sentence. Therefore, this is an incorrect option.
Option 2: A nephew is the son of an uncle or an aunt. This is perfectly appropriate in the context of the preceding sentence. As a result, this could be the right option.
Option 3: A niece is the daughter of an aunt or an uncle. This does not fit into the context of the above sentence. So, this can often be an incorrect option.
Option 4: A bride is also a female who is getting married. This will be completely unrelated to the above sentence. So, this will be an incorrect option.
Hence, option 2 is the correct option.

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