Find the energy required to split ${ }_8^{16}\mathrm{O}$ nucleus into four α –particles. The mass of an α –particle is 4.002603 u and that of oxygen is 15.994915 u.

The energy required to split O = 

[Total mass of the products - Total mass of the reactants] c²

$△E=\left[\right(4\times 4.002603)-15.994915]u\times c^2$

$=(0.015497)931.5\mathrm{MeV}=14.43\mathrm{MeV}$