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For sequencing, the total DNA from a cell is isolated and converted into random fragments of relatively smaller sizes because

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cloning results in amplification of DNA fragments

bacteria cannot take up longer fragments of DNA from the medium

the total number of estimated genes is 30,000

there are technical limitations in sequencing very long pieces of DNA

answer is D.

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For sequencing, the total DNA from a cell is isolated and converted into random fragments of relatively smaller sizes because there are technical limitations in sequencing very long pieces of DNA.

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