From the following list of statements about enzymes, labelled from I to V, pick the option with correct group of the statements
I) when $N{a}^{+},M{n}^{2+},C{o}^{2+},C{u}^{2+}$ are weakly bonded to enzyme molecules, increases catalytic activity
II) 310 K is the suitable temperature for enzyme – catalysed reactions in humans
III) Enzymes are highly active below optimum $P^H$ range
IV) One molecule of an enzyme may transform approximately one million molecules of the reactant per hour
V) Urease catalyses hydrolysis of amide linkages