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Q.

Given below are two statements: One is labelled Assertion(A) and other is labelled Reason(R).

Assertion(A): The gene I of human beings controls the the type of sugar associated with sugar polymer of RBC that protrudes out of the plasma membrane.

Reason(R): Gene I has three alleles found in human population.

In the light of above statements, choose the correct answer from the options given below.

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a

Both (A) and (R) are true and (R) is the correct explanation of (A)

b

Both (A) and (R) are true but (R) is not the correct explanation of (A)

c

(A) is true but (R) is false

d

Both (A) and (R) are false

answer is A.

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Detailed Solution

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Gene I of human beings determines the type of sugar that has to be associated with the oligosaccharide H substance of glycolipid of plasma membrane of RBC. It has three alleles IA, IB and i. IA attaches N-acetyl galactosamine to the H substance and IB attaches galactose, and allele ‘i’ does not attach any sugar to the H substance. H substance formation is under the control of gene H. H substance is trisaccharide and has galactose, N-acetyl glucosamine and fucose. Alleles IA and IB form two different forms of glycosyl transferases.

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