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Q.

Given below are two statements: One is labelled Assertion(A) and other is labelled Reason(R).

Assertion (A) : Sickle – cell anaemia is caused due to change of one amino acid in β − chain of haemoglobin.

Reason (R) : It occurs due to frameshift mutation.

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a

(A) and (R) both are true and the (R)  is correct explanation of (A)

b

(A) and (R)  both are true but (R)  is not correct explanation of (A)

c

(A) is true but (R) is wrong

d

(A) and (R)  both are wrong

answer is C.

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Detailed Solution

Sickle – cell anaemia is caused due to change of one amino acid in β − chain of haemoglobin. It is an example of transversion (point mutation).

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