Given below are two statements. One is labelled Assertion (A) and the other is labelled Reason (R).
Assertion (A) : Conversion of PEP into pyruvic acid is a substrate level phosphorylation reaction.
Reason (R) : ATP synthesis occurs during the formation of pyruvate from PEP utilizing the released phosphate.
In light of the above statements, choose the correct answer from the options given below.

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Both (A) and (R) are true and (R) is the correct explanation of (A).

Both (A) and (R) are true but (R) is not the correct explanation of (A).

(A) is true but (R) is false

Both (A) and (R) are false

answer is A.

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Detailed Solution

Assertion is true. Cytosolic pyruvate kinase catalyzes the transfer of a high-energy phosphate from phosphoenolpyruvate to ADP, forming pyruvate and ATP. This reaction, an instance of substrate-level phosphorylation.

Reason is also true. Substrate level phosphorylation is a mechanism of ATP formation involving the transfer of a phosphate(Pi) from a donor molecule to ADP to form ATP. This is exactly that happens during conversion of PEP to pyruvate.

Hence, assertion and reason are true and reason is the correct explanation for assertion.

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