Q.

Given below are two statements.
Statement I: Phenylketonuria is an example of pleiotropy.
Statement II: Phenylketonuria is associated with mental retardation, lighter skin, hair and eye colour.
In light of the above statements, choose the correct answer from the options given below.

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a

Statement I is correct but statement II is incorrect.

b

Both statement I and statement II are incorrect.

c

Statement I is incorrect but statement II is correct.

d

Both statement I and statement II are correct.

answer is C.

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Detailed Solution

An example of pleiotropy is the disease phenylketonuria, which occurs in humans. The disease is caused by a mutation in the gene that codes for the enzyme phenyl alanine hydroxylase (single gene mutation). This manifests itself through phenotypic expression characterised by mental retardation and a reduction in hair and skin pigmentation.

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Given below are two statements.Statement I: Phenylketonuria is an example of pleiotropy.Statement II: Phenylketonuria is associated with mental retardation, lighter skin, hair and eye colour.In light of the above statements, choose the correct answer from the options given below.