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Q.

Given below are two statements.

Statement I: Upon activation, cellular oncogenes transform into protooncogenes.

Statement II: α-interferon activates the immune system and helps in destroying the tumor.

choose the correct from the options given below.

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a

Both statement I and statement II are correct. 

b

Statement I is incorrect but statement II is correct. 

c

Statement I is correct but statement II is incorrect. 

d

Both statement I and statement II are incorrect.

answer is B.

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Detailed Solution

Statement I is false. Upon activation, cellular oncogenes do not transform into protooncogenes. In fact, it's the other way around. Proto-oncogenes are normal genes involved in cell growth and division, but when they undergo specific mutations or alterations, they can become oncogenes, which promote uncontrolled cell growth and cancer development. So, the correct statement would be that proto-oncogenes transform into oncogenes upon activation, not the other way around.

Statement II is true. α-interferon is a type of cytokine that plays a crucial role in activating the immune system's response against tumors. It helps in enhancing the activity of immune cells, such as natural killer cells and cytotoxic T cells, which are involved in recognising and destroying tumor cells. Therefore, α-interferon can indeed aid in tumor destruction by boosting the body's immune response against cancer.

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