Glucose has four chiral carbon atoms in its open chain structure. The absolute configuration in three of the chiral carbon atoms is ‘R’ whereas it is ‘S’ configuration at the other . The carbon atom with ‘S’ configuration is

C-2, C-3, C-3, C-4 are chiral centres;

-OH group is on the left side only at C-3, it has ‘S’ configuration;

Glucose is 2R,3S,4R,5R-2,3,4,5,6-pentahydroxy hexanal;

In ring structure chirality devoleps even at C-1 position or anomeric carbon;