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Q.

Hormones that interact with membrane-bound receptors

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a

regulate gene expression or chromosome function 

b

include thyroid hormones and steroid hormones 

c

are lipid-soluble and water-insoluble 

d

generate second messengers in target cells  

answer is D.

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Detailed Solution

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Water-soluble hormones cannot diffuse through the lipid bilayer of the target cells. They bind to receptors on the cell membrane. This leads to the generation of a second messenger (e.g., cAMP) inside the target cell which, in turn, regulates cellular metabolism. 
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Hormones that interact with membrane-bound receptors