How many of the following compounds can be used as an acetylating agent?I) CH3COCl II) (CH3 CO)2 O III) CH3COOH IV) CH3CH2COCl

Stronger the basic nature of the leaving group, weaker will be its leavability. In CH3COOH,OH- is strong base so, it can’t be removed easily to form 3 CH CO+ required foracetylation

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How many of the following compounds can be used as an acetylating agent?
I) CH₃COCl II) (CH3 CO)₂ O III) CH₃COOH IV) CH₃CH₂COCl

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answer is 3.

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Detailed Solution

Stronger the basic nature of the leaving group, weaker will be its leavability. In CH₃COOH,OH^- is strong base so, it can’t be removed easily to form 3 CH CO⁺ required for
acetylation

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