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Q.

Identify the conditions given below at the time when oxy-haemoglobin dissociation curve turns to the left.
a. Blood supplying O2 to tissues
b. A fall in pCO2 and rise in pH
c. Haemoglobin bound with O2 on the lung surface
d. A rise in pCO2 and fall in PH

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a

a - c - d

b

b - c – d

c

b - c

d

a - d

answer is C.

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Detailed Solution

A shift to the left indicates increased hemoglobin affinity for oxygen and an increased reluctance to release oxygen. Several physiologic factors are responsible for shifting the curve left or right, such as pH, carbon dioxide (CO2), temperature, and 2,3-Disphosphoglycerate.

The curve shift to the left when pO2 is high, PCO2 is low, temperature is low, pH is high and low 2,3-DPG.

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