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Q.

Identify the disease which is caused due to mutation in genes present on the X-chromosome.

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a

Colour blindness

b

Phenylketonuria

c

Sickle-cell anaemia

d

Thalassemia

answer is D.

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Detailed Solution

Colour blindness is a sex-linked recessive disorder due to defect in either red or green cone of eye resulting in failure to discriminate between red and green colour. This defect is due to mutation in certain genes present in the X chromosome.

Sickle-cell anaemia, phenylketonuria and thalassemia are autosomal recessive disorders caused due to genes present in the autosomes.

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Identify the disease which is caused due to mutation in genes present on the X-chromosome.