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Q.

If Meselson and Stahl's experiment is continued for four generations in bacteria, the ratio of 
15 N / 15 N : 15 N / 14 N : 14 N / 14 N containing DNA in the fourth generation would be

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a

1 : 1 : 0

b

1 : 4 : 0

c

0 : 1 : 3

d

0 : 1 : 7

answer is D.

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Detailed Solution

Option (d) is correct. 
Meselson and Stahl found that DNA of the first generation was hybrid or intermediate (15N and 14N). It settled in caesium chloride at a level higher than the fully labelled DNA of parent bacteria (15N and 15N). 
The second generation of bacteria after 40 minutes, contained two types of DNA , 50% light (N14 N14) and 50% intermediate (N15 N14).
The third generation of bacteria after 60 minutes contained two types of DNA ,25% intermediate (N15 N14) and 75% light (N14 N14) in 1 : 3 ratio.
It can be assumed that the fourth generation after 80 minutes would contain 12.5% N15 N14 and 87.5% N14 N14 DNA in 1 :7 ratio.
Thus, if Meselson and Stahl's experiment is continued for four generations in bacteria, the ratio of 15N / 15N : 15N and 14N : 14N and 14N containing DNA in the fourth generation would be 0 : 1 : 7.

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