Q.

In E. coli, there is a mutation in a gene called dnaB that alters the helicase that normally acts at the origin. Which of the following would you expect as a result of this mutation?
 

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a

Replication will occur via RNA polymerase

b

Replication will require a DNA template from another source.

c

No replication fork will be formed.

d

 No proof reading will occur.

answer is B.

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Detailed Solution

If there is a mutation in a gene called dnaB that alters the helicase, then the two strands of the DNA will not be separated and hence formation of replication fork will not take place. 

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