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Q.

In sickle cell anaemia, the substitution of amino acid in the globin protein results due to the single base substitution at the sixth codon of the beta globin gene from

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a

GUU to GTG

b

GAG to GUG

c

GTG to GUU

d

GUG to GAG

answer is B.

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Detailed Solution

In sickle cell anaemia, the substitution of amino acid in the globin protein results due to the single base substitution at the sixth codon of the beta globin gene from GAG to GUG.

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