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Q.

In the following human pedigree, the filled symbols represent affected individuals. Identify the type of disorder represented in the pedigree chart.

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a

Autosomal dominant

b

Autosomal recessive

c

X-linked dominant

d

X-linked recessive

answer is B.

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Detailed Solution

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The trait is seen in the first and fourth generations but not in the second and third generation. Only recessive traits skip generations. The trait is not X-linked recessive. In X-linked recessive inheritance, if a woman is affected, all her sons are affected. The woman in the first generation is affected but both of her sons are unaffected. Also in case of X-linked recessive inheritance, a woman can be affected only if her father is affected. The woman of the fourth generation is affected but her father is unaffected. So, the trait is not X-linked recessive. It is autosomal recessive

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