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In the kidney, the osmolarity increases from 300 mOsmL^-1 in the cortex to 1200 mOsmL^-1 in the medulla. This gradient is mainly due to

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An Intiative by Sri Chaitanya

NaCl and creatinine

Ketones and urea

HCO₃^- and Cl^-

NaCl and urea

answer is A.

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Detailed Solution

Increasing osmolarity towards the inner medullary interstitium, from 300mOsmL^–1 in the cortex to about 1200 mOsmL^–1 in the inner medulla is mainly caused by NaCl and urea.

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