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Q.

In the year 1963, the two enzymes responsible for restricting the growth of bacteriophage in Escherichio coli were isolated. They were _______ and ________ and respectively

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a

Ligase, Restriction endonuclease

b

Helicase, Restriction endonuclease

c

Methylase, Restriction endonuclease

d

DNA polymerase, Restriction endonuclease

answer is C.

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Detailed Solution

With respect to RM system, restriction endonuclease and methylase were discovered in 1962 by Werner Arber in bacteria attacked by bacteriophages.

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In the year 1963, the two enzymes responsible for restricting the growth of bacteriophage in Escherichio coli were isolated. They were _______ and ________ and respectively