In which stage of the cell cycle, are histone proteins synthesized in eukaryotic cells? 

Concept: Histone proteins are basic proteins that are rich in amino acids such as lysine and arginine. They are typically found in the nuclei of Eukaryotic cells, where they are packed and form the structural units nucleosomes. 

These proteins are synthesized during the s-phase of the cell cycle. The whole step of cell division is known as the cell cycle. Every cell cycle is a four-stage process, which includes G1, S, G2, and M phases. The S stage is for synthesis. In this stage, the hereditary material or the DNA gets replicated.

Hence, the correct answer is option B.