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Local anesthetics reduce pain by blocking nerve conduction. Which of the statement is correct pertaining to this process?

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${Na}^{+}$ channels are blocked more than $K^{+}$ channels

$K^{+}$ channels are blocked more than ${Na}^{+}$ channels

Both the kinds of channels are blocked equally

Neither of the channels are blocked

answer is A.

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Detailed Solution

Local anesthetics act on the voltage-gated sodium channels that conduct electrical impulses and mediate fast depolarization along nerves. They also act on potassium channels, but they block sodium channels more.

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